Recombinant Human MANF (C-6His)

Name: Recombinant Human MANF (C-6His)
SKU: RP00218
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00218 Tag : C-6His

Expressed Region : Leu25-Leu182 Expression System : Human Cell

Inquire for Price

Product Information

Gene Information

Cat. No.	RP00218
Description	The Recombinant Human MANF (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu25-Leu182 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	18.99 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Leu25-Leu182
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	MANF
Background	The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Synonyms	Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET; ARMET; ARP

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *