Recombinant Human KLK3 (236AA, C-6His)

Name: Recombinant Human KLK3 (236AA, C-6His)
SKU: RP00142

Cat.No. : RP00142 Tag: C-6His

Expressed Region: Ile25-Pro261 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00142
Description	The Recombinant Human KLK3 (236AA, C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ile25-Pro261 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	27.1 KDa
Expressed Region	Ile25-Pro261
Expression System	Human Cell
Format	Liquid
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Glycine-HCl, 150 mM NaCl, 20% Glycerol, 10 mM CaCl2, 0.05% Tween 80, pH3.0.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.

Target Gene	KLK3
Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Synonyms	Prostate-specific antigen; PSA; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS

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