Recombinant Human IGFBP2 (C-His)

Name: Recombinant Human IGFBP2 (C-His)
SKU: RP00668
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00668 Tag : C-His

Expressed Region : Ala36-Gln325 Expression System : Human Cell

Inquire for Price

Product Information

Gene Information

Cat. No.	RP00668
Description	The Recombinant Human IGFBP2 (C-His) is produced in our Human Cell expression system. The amino acid region expressed is Ala36-Gln325 with a His tag at the C terminus.
Species	Human
Tag	C-His
Mol Weight	33~35 kDa, on SDS-PAGE under reducing conditions.
Format	Powder
Expressed Region	Ala36-Gln325
Expression System	Human Cell
Formulation	Lyophilized after extensive dialysis against PBS.
Purity	> 95% as analyzed by SDS-PAGE
Endotoxin Level	< 0.2 EU/μg of protein by gel clotting method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	IGFBP2
Background	The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
Synonyms	IGF-BP-2, also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *