Recombinant Human IDO1 (N-6His)

Name: Recombinant Human IDO1 (N-6His)
SKU: RP00597
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00597 Tag : N-6His

Expressed Region : Met1-Gly403 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00597
Description	Recombinant Human IDO1 (N-6His) is produced in our E.coli expression system. The amino acid region expressed is Met1-Gly403 with a 6His tag at the N terminus.
Species	Human
Tag	N-6His
Mol Weight	46.8 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Met1-Gly403
Expression System	E.coli
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Sodium Acetate, 150mM NaCl, 20% Glycerol, pH 4.5.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	IDO1
Background	This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Synonyms	Indole 2;3-dioxygenase; Indoleamine 2;3-dioxygenase 1; IDO-1; IDO1; IDO; INDO

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