Pages
Products

Rat Ido1 cDNA Clone(NM_023973.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012228

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR012228
Description NativeORF clone of Rattus norvegicus indoleamine 2,3-dioxygenase 1 (Ido1) as transfection-ready DNA NM_023973.1
Product Type cDAN Clone
Gene Abbr Ido1
Species Rat
Vector pCMV6Entry
Target Gene IDO1
Background This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction