Recombinant Human GRB2 (C-6His)

Name: Recombinant Human GRB2 (C-6His)
SKU: RP00213
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00213 Tag : C-6His

Expressed Region : Met1-Val217 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00213
Description	The Recombinant Human GRB2 (C-6His) is produced in our E.coli expression system. The amino acid region expressed is Met1-Val217 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	26.3 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Val217
Expression System	E.coli
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 6% Sucrose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	GRB2
Background	The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	Growth Factor Receptor-Bound Protein 2; Adapter Protein GRB2; Protein Ash; SH2/SH3 Adapter GRB2; GRB2; ASH

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