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Cat. No. : RP00242 Tag : C-6His
Expressed Region : Ile22-Val235 Expression System : Human Cell
| Cat. No. | RP00242 |
| Description | The Recombinant Human GPA33 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ile22-Val235 with a 6His tag at the C terminus. |
| Species | Human |
| Tag | C-6His |
| Mol Weight | 24.66 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Ile22-Val235 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1mM EDTA, pH7.2. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | GPA33 |
| Background | The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. |
| Synonyms | Cell Surface A33 Antigen; Glycoprotein A33; GPA33 |
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