Recombinant Human CD44 (C-6His)

Name: Recombinant Human CD44 (C-6His)
SKU: RP00174
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00174 Tag : C-6His

Expressed Region : Gln21-Pro220 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00174
Description	The Recombinant Human CD44 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln21-Pro220 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	23.1 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Gln21-Pro220
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	CD44
Synonyms	CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 Lymphocyte Homing/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I; CD44; LHR; MDU2; MDU3; MIC4

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The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

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