Recombinant Human CD105 (N-Trx-6His)

Name: Recombinant Human CD105 (N-Trx-6His)
SKU: RP00490
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00490 Tag : N-Trx, 6His

Expressed Region : Glu26-Gln176(Gly40Asp) Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00490
Description	Recombinant Human CD105 (N-Trx-6His) is produced in our E.coli expression system. The amino acid region expressed is Glu26-Gln176(Gly40Asp) with a Trx, 6His tag at the N terminus.
Species	Human
Tag	N-Trx, 6His
Mol Weight	33.6 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Glu26-Gln176(Gly40Asp)
Expression System	E.coli
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	CD105
Background	This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	Endoglin; END; CD105; ENG

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