Recombinant Human BRD4 (N-10His-Flag)

Name: Recombinant Human BRD4 (N-10His-Flag)
SKU: RP00226
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00226 Tag : N-10His-Flag

Expressed Region : Glu49-Glu460 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00226
Description	The Recombinant Human BRD4 (N-10His-Flag) is produced in our E.coli expression system. The amino acid region expressed is Glu49-Glu460 with a 10His-Flag tag at the N terminus.
Species	Human
Tag	N-10His-Flag
Mol Weight	49 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Glu49-Glu460
Expression System	E.coli
Formulation	Supplied as a 0.2 μm filtered solution of 50mM HEPES, 200mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	BRD4
Background	The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Synonyms	HUNK1; bromodomain-containing protein 4; HUNKI; MCAP

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