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Cat. No. : RP00268 Tag : C-Fc
Expressed Region : Arg28-Asn763 Expression System : Human Cell
| Cat. No. | RP00268 |
| Description | The Recombinant Human AOC3 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Arg28-Asn763 with a Fc tag at the C terminus. |
| Species | Human |
| Tag | C-Fc |
| Mol Weight | 108.5 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Arg28-Asn763 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, pH 8.0. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | AOC3 |
| Background | This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. |
| Synonyms | Membrane primary amine oxidase; Copper amine oxidase; Semicarbazide-sensitive amine oxidase; Vascular adhesion protein 1; AOC3; VAP-1; SSAO; HPAO |
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