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CC-965

NPY Easy KO Kit (Mouse)

For research use only. Not intended for any clinical use.

Cat. No. :   CC-965

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Product Information

Gene Information

Cat. No. CC-965
Description A complete kit for efficient gene knockout in mammalian cells, combining chemically synthesized sgRNAs with Cas9 RNPs to induce targeted DNA cleavage and generate frameshift mutations or deletions. All essential reagents for transfection and knockout validation are included for rapid, high-efficiency gene disruption.
Gene Abbr Npy
Gene Name Npy neuropeptide Y [ Mus musculus ]
Species Mouse
Ensembl ID ENSMUSG00000029819
NCBIGene ID 109648
Uni Prot ID P57774
Features
  • All-in-One workflow from gene editing to knockout validation for users with no prior experience.
  • Pre-validated sgRNAs and primers for rapid setup.
  • Streamlined experiment handling.
  • CRISPR RNP method ensures precise and efficient gene knockout.
Applications This kit enables in vitro gene knockout in human-derived cells using chemically synthesized sgRNAs and Cas9-gRNA RNP complexes. Transfected RNPs cleave early exons of the target gene, inducing deletions or frameshift mutations for efficient and rapid knockout.
Reactions 5–10 reactions per target gene
Kit Components 2–3 chemically synthesized sgRNAs (200pmol each)
3 PCR/Sequencing primers (500pmol each)
LM cell lysate (500µL)
Cas9 protein (12µg)
LM RNP transfection reagent (50µL)
Storage Store at -80°C for up to 1 year or at -20°C for up to 6 months. Avoid repeated freeze-thaw cycles.
Gene Name Npy neuropeptide Y [ Mus musculus ]
Gene Symbol Npy
Synonyms 0710005A05Rik
Gene Description neuropeptide Y
Gene ID 109648
Uni Prot ID P57774
m RNA Refseq NM_023456.2
Protein Refseq NP_075945.1
Chromosome Location 6 B3; 6 26.0 cM
Function G-protein coupled receptor binding; G-protein coupled receptor binding; hormone activity; neuropeptide Y receptor binding;
Pathway Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
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