ITGB3 Easy KO Kit (Mouse)

Name: ITGB3 Easy KO Kit (Mouse)
SKU: CC-716
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CC-716

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Product Information

Gene Information

Cat. No.	CC-716
Description	A complete kit for efficient gene knockout in mammalian cells, combining chemically synthesized sgRNAs with Cas9 RNPs to induce targeted DNA cleavage and generate frameshift mutations or deletions. All essential reagents for transfection and knockout validation are included for rapid, high-efficiency gene disruption.
Gene Abbr	Itgb3
Gene Name	Itgb3 integrin beta 3 [ Mus musculus ]
Species	Mouse
EnsemblID	ENSMUSG00000020689
NCBIGeneID	16416
Uni ProtID	O54890
Features	All-in-One workflow from gene editing to knockout validation for users with no prior experience. Pre-validated sgRNAs and primers for rapid setup. Streamlined experiment handling. CRISPR RNP method ensures precise and efficient gene knockout.
Applications	This kit enables in vitro gene knockout in human-derived cells using chemically synthesized sgRNAs and Cas9-gRNA RNP complexes. Transfected RNPs cleave early exons of the target gene, inducing deletions or frameshift mutations for efficient and rapid knockout.
Reactions	5–10 reactions per target gene
Kit Components	2–3 chemically synthesized sgRNAs (200pmol each) 3 PCR/Sequencing primers (500pmol each) LM cell lysate (500µL) Cas9 protein (12µg) LM RNP transfection reagent (50µL)
Storage	Store at -80°C for up to 1 year or at -20°C for up to 6 months. Avoid repeated freeze-thaw cycles.

Gene Name	Itgb3 integrin beta 3 [ Mus musculus ]
Gene Symbol	Itgb3
Synonyms	CD61; GP3A; INGRB3
Gene Description	integrin beta 3
GeneID	16416
Uni ProtID	O54890
mRNA Refseq	NM_016780.2
Protein Refseq	NP_058060.2
Chromosome Location	11 E1; 11 68.0 cM
Function	cell adhesion molecule binding; contributes_to fibrinogen binding; identical protein binding; integrin binding; peptide binding; protein binding; protein disulfide isomerase activity; receptor activity; receptor binding; vascular endothelial growth factor receptor 2 binding;
Pathway	Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; ECM-receptor interaction, organism-specific biosystem;

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