IRF1 Easy KO Kit (Human)

Name: IRF1 Easy KO Kit (Human)
SKU: CC-703
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CC-703

Inquire for Price

Product Information

Gene Information

Cat. No.	CC-703
Description	A complete kit for efficient gene knockout in mammalian cells, combining chemically synthesized sgRNAs with Cas9 RNPs to induce targeted DNA cleavage and generate frameshift mutations or deletions. All essential reagents for transfection and knockout validation are included for rapid, high-efficiency gene disruption.
Gene Abbr	Irf1
Gene Name	IRF1 interferon regulatory factor 1 [ Homo sapiens ]
Species	Human
EnsemblID	ENSMUSG00000018899
NCBIGeneID	16362
Uni ProtID	P15314
Features	All-in-One workflow from gene editing to knockout validation for users with no prior experience. Pre-validated sgRNAs and primers for rapid setup. Streamlined experiment handling. CRISPR RNP method ensures precise and efficient gene knockout.
Applications	This kit enables in vitro gene knockout in human-derived cells using chemically synthesized sgRNAs and Cas9-gRNA RNP complexes. Transfected RNPs cleave early exons of the target gene, inducing deletions or frameshift mutations for efficient and rapid knockout.
Reactions	5–10 reactions per target gene
Kit Components	2–3 chemically synthesized sgRNAs (200pmol each) 3 PCR/Sequencing primers (500pmol each) LM cell lysate (500µL) Cas9 protein (12µg) LM RNP transfection reagent (50µL)
Storage	Store at -80°C for up to 1 year or at -20°C for up to 6 months. Avoid repeated freeze-thaw cycles.

Gene Name	IRF1 interferon regulatory factor 1 [ Homo sapiens ]
Gene Symbol	IRF1
Synonyms	MAR; IRF-1
GeneID	3659
Uni ProtID	P10914
mRNA Refseq	NM_002198.2
Protein Refseq	NP_002189.1
Chromosome Location	5q31.1
Function	DNA binding; protein binding; regulatory region DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway	Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
MIM	147575

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *