Human STUB1 Knockout Cell Line-HEK293

Name: Human STUB1 Knockout Cell Line-HEK293
SKU: CSC-RT2823
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RT2823

Target Gene : STUB1 Host Cell : HEK293

Size : >1x10⁶ cells/vial Validation : Sequencing

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RT2823
Description	This cell is a stable cell line with a homozygous knockout of human STUB1 using CRISPR/Cas9.
Target Gene	STUB1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Size	1 vial (>10^6 cell/vial)
Validation	Sequencing
Storage	Liquid Nitrogen
Shipping	Dry ice package

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol	STUB1
Synonyms	CHIP; UBOX1; HSPABP2; NY-CO-7; SDCCAG7
Gene Description	STIP1 homology and U-box containing protein 1
Gene ID	10273
Uni Prot ID	Q9UNE7
m RNA Refseq	NM_005861.2
Protein Refseq	NP_005852.2
Chromosome Location	16p13.3
Function	Hsp70 protein binding; Hsp90 protein binding; SMAD binding; TPR domain binding; enzyme binding; kinase binding; misfolded protein binding; protein binding; protein binding, bridging; protein homodimerization activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-ubiquitin ligase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
MIM	607207

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