Panoply™ Human STUB1 Knockdown Stable Cell Line

Name: Panoply™ Human STUB1 Knockdown Stable Cell Line
SKU: CSC-DC015351
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015351

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015351
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	STUB1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol	STUB1
Synonyms	CHIP; UBOX1; HSPABP2; NY-CO-7; SDCCAG7
Gene Description	STIP1 homology and U-box containing protein 1
Gene ID	10273
Uni Prot ID	Q9UNE7
m RNA Refseq	NM_005861.2
Protein Refseq	NP_005852.2
Chromosome Location	16p13.3
Function	Hsp70 protein binding; Hsp90 protein binding; SMAD binding; TPR domain binding; enzyme binding; kinase binding; misfolded protein binding; protein binding; protein binding, bridging; protein homodimerization activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-ubiquitin ligase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
MIM	607207

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