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Human PTH2R Nanodisc

For research use only. Not intended for any clinical use.

Cat. No. :   OE-PNDC000525

Tag :   C-Flag tag and Strep Tag Expression System :   Mammalian expression system

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Gene Information

Cat. No. OE-PNDC000525
Description Human PTH2R nanodisc contains full length human PTH2R protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human PTH2R protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human PTH2R membrane protein.
Gene Abbr PTH2R
Gene Name PTH2R
Species Human
Gene Species Human
Tag C-Flag tag and Strep Tag
Features 1) Full-length membrane protein
2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications
3) Maintaining the native spatial conformation and activity of the membrane protein
4) Possessing high solubility and stability
5) High purity determined by HPLC
6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications 1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment.
2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins.
3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins.
4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format Lyophilized protein
Expression System Mammalian expression system
Note For Research Use Only.
Storage Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping Lyophilized proteins are shipped under ambient temperature conditions.
Target Gene PTH2R
Background The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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