Human HCN2 Nanodisc

Name: Human HCN2 Nanodisc
SKU: OE-PNDC000354
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : OE-PNDC000354

Tag : C-Flag tag and Strep Tag Expression System : Mammalian expression system

Inquire for Price

Product Information

Gene Information

Cat. No.	OE-PNDC000354
Description	Human HCN2 nanodisc contains full length human HCN2 protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human HCN2 protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human HCN2 membrane protein.
Gene Abbr	HCN2
Gene Name	HCN2
Species	Human
Gene Species	Human
Tag	C-Flag tag and Strep Tag
Features	1) Full-length membrane protein 2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications 3) Maintaining the native spatial conformation and activity of the membrane protein 4) Possessing high solubility and stability 5) High purity determined by HPLC 6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications	1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment. 2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins. 3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins. 4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format	Lyophilized protein
Expression System	Mammalian expression system
Note	For Research Use Only.
Storage	Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping	Lyophilized proteins are shipped under ambient temperature conditions.

Target Gene

Hcn2

Background

Predicted to enable several functions, including PDZ domain binding activity; identical protein binding activity; and monoatomic cation channel activity. Acts upstream of or within regulation of membrane potential. Located in membrane. Is expressed in central nervous system and heart. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2). [provided by Alliance of Genome Resources, Feb 2025]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *