Human CACNA1G Nanodisc

Name: Human CACNA1G Nanodisc
SKU: OE-PNDC000344
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : OE-PNDC000344

Tag : C-Flag tag and Strep Tag Expression System : Mammalian expression system

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Product Information

Gene Information

Cat. No.	OE-PNDC000344
Description	Human CACNA1G nanodisc contains full length human CACNA1G protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human CACNA1G protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human CACNA1G membrane protein.
Gene Abbr	CACNA1G
Gene Name	CACNA1G
Species	Human
Gene Species	Human
Tag	C-Flag tag and Strep Tag
Features	1) Full-length membrane protein 2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications 3) Maintaining the native spatial conformation and activity of the membrane protein 4) Possessing high solubility and stability 5) High purity determined by HPLC 6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications	1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment. 2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins. 3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins. 4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format	Lyophilized protein
Expression System	Mammalian expression system
Note	For Research Use Only.
Storage	Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping	Lyophilized proteins are shipped under ambient temperature conditions.

Target Gene

CACNA1G

Background

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]

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