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Mayaro Virus-Like Particle

For research use only. Not intended for any clinical use.
Cat.No.
VLP-0009
Description
Non-infectious Mayaro Virus-Like Particles consist of E1, E2 and capsid proteins without genome. The VLPs are produced in HEK293 cells.
Shipping
Dry ice
Storage
-80˚C

Background

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Q & A

Customer Reviews

Mayaro virus is an enveloped virus and has an icosahedral capsid with a diameter of 70 nm. The virus genome is composed of a linear, positive-sense, single-stranded RNA with 11,429 nucleotides, excluding the 5’ cap nucleotide and 3’ poly(A) tail. The virus RNA genome contains the 5' untranslated region, 3' noncoding region, and two open reading frames (ORFs). The 5’-proximal ORF codes for a polyprotein that after cleavage forms nonstructural proteins (nsP1, nsP2, nsP3, nsP4) and the 3’-proximal ORF with a 26S promoter codes for a polyprotein that is cleaved into structural proteins to generate capsid proteins and envelope surface glycoproteins (E1, E2, E3, C, 6K).
Customer Q&As
What is Mayaro virus (MAYV)?

A: Mayaro virus (MAYV) is a positive-sense single stranded RNA virus that belongs to the genus Alphavirus, a member of the Togaviridae family of viruses. It is a member of the Semliki Forest antigenic sero-complex, a serological group within the Alphavirus genus, and is closely related to Chikungunya virus

How are Mayaro Virus-Like Particles produced?

A: At Creative Biogene, we have prepared recombinant Mayaro Virus VLP utilising our proprietary mammalian cell expression system. These particles contain Capsid and E1 and E2 envelope proteins. They will find application for researchers and assay developers who are looking to develop assays to distinguish Mayaro virus infection from Chikugunya virus.

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Customer Reviews
Easy to Work

The quality of the particles was excellent, and they were easy to work with. I highly recommend this product to fellow researchers looking to study Mayaro virus.

United States

12/15/2022

Worth Buying

The detailed protocols provided by the manufacturer were extremely helpful, making it easy to integrate the particles into our experimental workflow. I am highly impressed with this product and its performance and would definitely purchase it again.

United States

03/27/2023

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