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Dengue Virus-Like Particle (Serotype 2)

For research use only. Not intended for any clinical use.
Cat.No.
VLP-0003
Description
Non-infectious Dengue Virus serotype 2 virus-like particles consist of Membrane, pre-Membrane and Envelope proteins. The VLPs are produced in HEK293 cells.
Background
The DENV genome is about 11000 bases of positive-sense, single stranded RNA (ssRNA) that codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS-1, -2a, -2b, -3, -4a, -4b, -5). It also includes short noncoding regions on both the 5' and 3' ends. Dengue virus (DENV) is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes (1,2,3 and 4) of the virus have been found.
Shipping
Dry ice
Storage
-80˚C

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Customer Q&As
What is the difference between Dengue Virus-Like Particle (Serotype 2) and Serotype 1?

A: The difference between Dengue Virus-Like Particle (Serotype 2) and Serotype 1 lies in the specific serotype of the dengue virus they belong to. Dengue viruses are categorized into four serotypes: serotype 1, serotype 2, serotype 3, and serotype 4. Each serotype represents a distinct strain or subtype of the virus with different antigenic properties.

What are the advantages of using Dengue virus-like particles (VLPs) in vaccine development?

A: Using Dengue VLPs as a vaccine has several advantages. Firstly, as VLPs lack the viral genetic material, there is no risk of causing the disease. Secondly, VLPs mimic the structure of the virus, making them highly immunogenic and able to stimulate a robust immune response. Lastly, VLPs can be produced using recombinant DNA technology, allowing for large-scale production and potential cost-effective vaccine manufacturing.

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Customer Reviews
High Immunological Activity

Dengue Virus-Like Particle (Serotype 2) products are able to effectively activate key aspects of the immune response to achieve effective immune stimulation and provide immune memory.

United States

07/24/2023

High Quality Product

The product is concentrated and purified by a series of ultracentrifugation and chromatographic methods to provide excellent purity and quality.

United States

03/28/2022

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