Luciferase Reporter Cell Line - RL

In 1893, Dan L. Longo and Walter J. Urba established the RL cell line from the ascites of a 52-year-old Caucasian male diagnosed with non-Hodgkin lymphoma (NHL) affecting B cells. Since then, RL cells have been used as a model for studying B-cell NHL. This cell line is valuable in the field of cancer research, especially for studies focusing on the pathology, molecular biology, and treatment of lymphomas. GFP Reporter Cell Line - RL is a genetically engineered cell line that stably expresses the green fluorescent protein (GFP) reporter gene within RL cells. Stable expression of GFP ensures consistent and reproducible results, eliminating the variability associated with transient transfection methods. The bright fluorescence emitted by GFP can be easily detected using standard fluorescence microscopy, flow cytometry, and other imaging techniques. In addition, GFP Reporter Cell Line - RL facilitates high-throughput screening and real-time tracking of cellular events, which is important for drug discovery, gene regulation studies, and understanding the mechanisms underlying disease progression.