Humanized PLAUR Murine Tumor Cell Line

Name: Humanized PLAUR Murine Tumor Cell Line
SKU: CSC-RH0035M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0035M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0035M
Description	This cell line is engineered to stably express chimeric PLAUR containing mouse signal peptide and human coding sequence. The endogenous mouse Plaur gene was disrupted, resulting in a non-functional transcript.
Target Gene	PLAUR
Alias	CD87, U-PAR, UPAR, URKR
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PLAUR plasminogen activator, urokinase receptor [ Homo sapiens ]
Gene Symbol	PLAUR
Synonyms	PLAUR; plasminogen activator, urokinase receptor; urokinase plasminogen activator surface receptor; CD87; UPAR; URKR; urokinase type plasminogen activator (uPA) receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor; U-PAR;
GeneID	5329
Uni ProtID	Q03405
mRNA Refseq	BC002788
Chromosome Location	19q13
Function	U-plasminogen activator receptor activity; enzyme binding; protein binding; receptor activity;
Pathway	Arf6 downstream pathway, organism-specific biosystem; Attachment of GPI anchor to uPAR, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem;
MIM	173391

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