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PLAUR


Official Full Name
plasminogen activator, urokinase receptor
Organism
Homo sapiens
Gene ID
5329
Background
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Synonyms
CD87; UPAR; URKR; U-PAR

Cat.No. Product Name Price
SHH377060 shRNA set against Human PLAUR (NM_002659.3) Inquiry
SHH377064 shRNA set against Mouse PLAUR (NM_011113.3) Inquiry
SHH377068 shRNA set against Rat PLAUR (NM_017350.1) Inquiry
Cat.No. Product Name Price
CDCG002281 Rat PLAUR ORF clone(NM_017350.1) Inquiry
CDFL010391 Mouse Plaur cDNA Clone(NM_011113.3) Inquiry
CDFR014151 Rat Plaur cDNA Clone(NM_134352.1) Inquiry
MiUTR1M-09296 PLAUR miRNA 3'UTR clone Inquiry
MiUTR1R-05890 PLAUR miRNA 3'UTR clone Inquiry
MiUTR1R-05891 PLAUR miRNA 3'UTR clone Inquiry
MiUTR3H-01774 PLAUR miRNA 3'UTR clone Inquiry
MiUTR3H-01775 PLAUR miRNA 3'UTR clone Inquiry
MiUTR3H-01776 PLAUR miRNA 3'UTR clone Inquiry
SKO0678 PLAUR Validated sgRNA vector Inquiry
CDCB195449 Rabbit PLAUR ORF clone (XM_008251279.1) Inquiry
CDCL185744 Mouse PLAUR ORF clone(NM_011113.3) Inquiry
CDCR381036 Rat Plaur ORF Clone(NM_134352.1) Inquiry
CDCS406244 Human PLAUR ORF Clone (BC002788) Inquiry
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