Humanized MMP8 Murine Tumor Cell Line

Name: Humanized MMP8 Murine Tumor Cell Line
SKU: CSC-RH0005M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0005M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

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Gene Information

Cat. No.	CSC-RH0005M
Description	These transgenic cells carry humanized MMP8 and form solid tumors in vivo. The endogenous mouse Mmp8 gene was replaced by human MMP8 gene.
Target Gene	MMP8
Alias	CLG1, HNC, MMP-8, PMNL-CL
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MMP8 matrix metallopeptidase 8 (neutrophil collagenase) [ Homo sapiens ]
Gene Symbol	MMP8
Synonyms	HNC; CLG1; MMP-8; PMNL-CL
GeneID	4317
Uni ProtID	P22894
mRNA Refseq	NM_002424.2
Protein Refseq	NP_002415.1
Chromosome Location	11q22.3
Function	calcium ion binding; metalloendopeptidase activity; serine-type endopeptidase activity; zinc ion binding;
Pathway	Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
MIM	120355

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