Humanized CCL2 Murine Tumor Cell Line

Name: Humanized CCL2 Murine Tumor Cell Line
SKU: CSC-RH0040M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0040M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0040M
Description	These transgenic cells carry humanized CCL2 and form solid tumors in vivo. The endogenous mouse Ccl2 gene was replaced by human CCL2 gene.
Target Gene	CCL2
Alias	HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CCL2 chemokine (C-C motif) ligand 2 [ Homo sapiens ]
Gene Symbol	CCL2
Synonyms	HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Gene Description	chemokine (C-C motif) ligand 2
Gene ID	6347
Uni Prot ID	P13500
m RNA Refseq	NM_002982.3
Protein Refseq	NP_002973.1
Chromosome Location	17q11.2-q12
Function	CCR2 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity; heparin binding; protein kinase activity; receptor binding;
Pathway	Activation of Genes by ATF4, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
MIM	158105

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