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Human BMPR1B mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0250
Description
The BMPR1B mRNA encodes the human bone morphogenetic protein receptor type 1B (BMPR1B) protein, a family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis.
Alias
ALK6; AMDD; BDA2; ALK-6; BDA1D; CDw293
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHRALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDAKS MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD TNEVDIPPNT RVGTKRYMPP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS RLTALRVKKT LAKMSESQDI KL
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Customer Q&As
What is Human BMPR1B mRNA?

A: BMPR1B mRNA is an RNA molecule in the human body that is the transcription product of the BMPR1B gene and can encode the BMPR1B protein.

What kind of protein does the BMPR1B gene encode?

A: BMPR1B gene Encodes a protein called bone morphogenetic protein receptor 1B (BMPR1B), which is a receptor tyrosine kinase involved in cellular signaling pathways.

What is the role of BMPR1BmRNA in the human body?

A: BMPR1B mRNA encodes the BMPR1B protein that is involved in many physiological processes in the human body, such as bone development, muscle growth, and angiogenesis.

What is the expression pattern of the BMPR1B gene?

A: The expression pattern of the BMPR1B gene varies in different tissues and cell types, and its expression in the human body is mainly concentrated in tissues such as bone, muscle, and cardiovascular system.

What is the stability of BMPR1B mRNA?

A: The stability of BMPR1B mRNA is affected by several factors, such as RNA structure and post-transcriptional modifications. Generally, it has a half-life between a few hours and a few days.

What are the consequences of a mutation in the BMPR1B gene?

A: Mutations in the BMPR1B gene may lead to changes in the structure and function of the BMPR1B protein, which in turn may affect physiological processes such as bone development and muscle growth in the human body, and may even lead to some diseases.

How to detect the expression level of BMPR1B mRNA?

A: Some molecular biology techniques such as RT-PCR, Northernblotting, insituhybridization can be used to detect the expression level of BMPR1B mRNA.

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