human SIRT1 ORF clone (NM_001142498.1)

Name: human SIRT1 ORF clone (NM_001142498.1)
SKU: CDCH080402
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH080402

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Product Information

Gene Information

Cat. No.	CDCH080402
Description	Homo sapiens sirtuin 1 (SIRT1), transcript variant 2, mRNA.
Product Type	ORF clone
Gene Abbr	SIRT1
Gene Name	SIRT1 sirtuin 1 [ Homo sapiens ]
Species	Human
ORF Size	1359bp
Format	purified plasmid or bacterial stock
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Gene Name	SIRT1 sirtuin 1 [ Homo sapiens ]
Gene Symbol	SIRT1
Synonyms	SIR2L1
Gene Description	sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
GeneID	23411
Uni ProtID	A8K128
mRNA Refseq	NM_001142498.1
Protein Refseq	NP_001135970.1
Chromosome Location	10q21.3
Function	HLH domain binding; NOT NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent protein deacetylase activity; NAD-dependent protein deacetylase activity; bHLH transcription factor binding; deacetylase activity; histone binding; histone deacetylase activity; identical protein binding; metal ion binding; mitogen-activated protein kinase binding; p53 binding; protein C-terminus binding; protein binding; protein deacetylase activity; transcription corepressor activity; transcription corepressor activity;
Pathway	Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; E2F transcription factor network, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem;
MIM	604479

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