human SGK1 ORF clone (NM_001143678.1)

Name: human SGK1 ORF clone (NM_001143678.1)
SKU: CDCH079512
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH079512

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Product Information

Gene Information

Cat. No.	CDCH079512
Description	Homo sapiens serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 4, mRNA.
Product Type	ORF clone
Gene Abbr	SGK1
Species	Human
ORF Size	1338bp
Format	purified plasmid or bacterial stock
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

SGK1

Background

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

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