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human RNF6 (NM_005977) lentivirus particles

For research use only. Not intended for any clinical use.

Cat. No. :   LV24206L

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

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Gene Information

Cat. No. LV24206L
Description Lentiviral particles of ring finger protein (C3H2C3 type) 6 (RNF6), transcript variant 1.
Product Type Premade Lentivirus Particles
Gene RNF6
Species Human
Insert Size 2058 bp
Titer Varies lot by lot, for example, ≥1*10^7 TU/mL, ≥1*10^8 TU/mL, ≥1*10^9 TU/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.
Gene Name RNF6 ring finger protein (C3H2C3 type) 6 [ Homo sapiens ]
Gene Symbol RNF6
Synonyms RNF6; ring finger protein (C3H2C3 type) 6; E3 ubiquitin-protein ligase RNF6; DKFZp686P0776; RING H2 protein RNF 6; RING-H2 protein RNF-6;
Gene ID 6049
Uni Prot ID Q9Y252
m RNA Refseq BC034688
Chromosome Location 13q12.2
Function DNA binding; androgen receptor binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
MIM 604242
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  1. Liu Y, Chen P, Qi D, et al. Glaucocalyxin A inhibits the malignancies of gastric cancer cells by downregulating MDM2 and RNF6 via MiR-3658 and the SMG1-UPF mRNA decay pathway[J]. Frontiers in Oncology, 2022, 12: 871169.
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