human PPARGC1B (NM_133263) lentivirus particles

Name: human PPARGC1B (NM_133263) lentivirus particles
SKU: LV22330L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV22330L

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV22330L
Description	Lentiviral particles of peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 1.
Product Type	Premade Lentivirus Particles
Gene	PPARGC1B
Species	Human
Insert Size	3072 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta [ Homo sapiens ]
Gene Symbol	PPARGC1B
Synonyms	PERC; ERRL1; PGC1B; PGC-1(beta)
Gene Description	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
GeneID	133522
Uni ProtID	Q86YN6
mRNA Refseq	NM_133263.3
Protein Refseq	NP_573570.3
Chromosome Location	5q32
Function	AF-2 domain binding; RNA binding; RNA polymerase II transcription cofactor activity; estrogen receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nucleotide binding; receptor activator activity;
Pathway	AMPK signaling, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Gene Expression, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem;
MIM	608886

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