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human HDAC4 (NM_006037) lentivirus particles

For research use only. Not intended for any clinical use.

Cat. No. :   LV14460L

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. LV14460L
Description Lentiviral particles of histone deacetylase 4 (HDAC4).
Product Type Premade Lentivirus Particles
Gene HDAC4
Species Human
Insert Size 3255 bp
Titer Varies lot by lot, for example, ≥1*10^7 TU/mL, ≥1*10^8 TU/mL, ≥1*10^9 TU/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.
Gene Name HDAC4 histone deacetylase 4 [ Homo sapiens ]
Gene Symbol HDAC4
Synonyms HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A
Gene Description histone deacetylase 4
Gene ID 9759
Uni Prot ID P56524
m RNA Refseq NM_006037.3
Protein Refseq NP_006028.2
Chromosome Location 2q37.3
Function NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); activating transcription factor binding; histone deacetylase activity; histone deacetylase binding; potassium ion binding; protein binding; protein deacetylase activity; repressing transcription factor binding; contributes_to sequence-specific DNA binding; transcription factor binding; contributes_to transcription regulatory region DNA binding; zinc ion binding;
Pathway Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Cell cycle, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem;
MIM 605314
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