human GRIN1 (NM_001185091) lentivirus particles

Name: human GRIN1 (NM_001185091) lentivirus particles
SKU: LV14125L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV14125L

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV14125L
Description	Lentiviral particles of glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant 5.
Product Type	Premade Lentivirus Particles
Gene	GRIN1
Species	Human
Insert Size	2721 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 [ Homo sapiens ]
Gene Symbol	GRIN1
Synonyms	NR1; MRD8; GluN1; NMDA1; NMDAR1
Gene ID	2902
Uni Prot ID	Q05586
m RNA Refseq	NM_000832.6
Protein Refseq	NP_000823.4
Chromosome Location	9q34.3
Function	contributes_to N-methyl-D-aspartate selective glutamate receptor activity; contributes_to calcium channel activity; calcium ion binding; calmodulin binding; extracellular-glutamate-gated ion channel activity; glutamate binding; glycine binding; glycine binding; neurotransmitter binding; protein binding; receptor binding;
Pathway	Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem;
MIM	138249

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