human GCHFR (NM_005258) lentivirus particles

Name: human GCHFR (NM_005258) lentivirus particles
SKU: LV13449L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV13449L

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV13449L
Description	Lentiviral particles of GTP cyclohydrolase I feedback regulator (GCHFR).
Product Type	Premade Lentivirus Particles
Gene	GCHFR
Species	Human
Insert Size	255 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	GCHFR GTP cyclohydrolase I feedback regulator [ Homo sapiens ]
Gene Symbol	GCHFR
Synonyms	P35; GFRP; HsT16933
Gene Description	GTP cyclohydrolase I feedback regulator
GeneID	2644
Uni ProtID	P30047
mRNA Refseq	NM_005258.2
Protein Refseq	NP_005249.1
Chromosome Location	15q15
Function	GTP-dependent protein binding; amino acid binding; enzyme binding; enzyme inhibitor activity; protein binding;
Pathway	Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem;
MIM	602437

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