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human DOCK11 (NM_144658) lentivirus particles

For research use only. Not intended for any clinical use.

Cat. No. :   LV11048L

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. LV11048L
Description Lentiviral particles of dedicator of cytokinesis 11 (DOCK11).
Product Type Premade Lentivirus Particles
Gene DOCK11
Species Human
Insert Size 6222 bp
Titer Varies lot by lot, for example, ≥1*10^7 TU/mL, ≥1*10^8 TU/mL, ≥1*10^9 TU/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.
Gene Name DOCK11 dedicator of cytokinesis 11 [ Homo sapiens ]
Gene Symbol DOCK11
Synonyms ACG; ZIZ2; bB128O4.1
Gene Description dedicator of cytokinesis 11
GeneID 139818
Uni ProtID Q5JSL3
mRNA Refseq NM_144658.3
Protein Refseq NP_653259.3
Chromosome Location Xq24
Function GTP binding; Rho GTPase binding; Rho guanyl-nucleotide exchange factor activity; phospholipid binding;
Pathway Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Regulation of CDC42 activity, organism-specific biosystem;
MIM 300681
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