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Dengue Virus-Like Particle (Serotype 1)

For research use only. Not intended for any clinical use.
Cat.No.
VLP-0002
Description
Non-infectious Dengue Virus serotype 1 virus-like particles consist of Membrane, pre-Membrane and Envelope proteins. The VLPs are produced in HEK293 cells.
Background
The DENV genome is about 11000 bases of positive-sense, single stranded RNA (ssRNA) that codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS-1, -2a, -2b, -3, -4a, -4b, -5). It also includes short noncoding regions on both the 5' and 3' ends. Dengue virus (DENV) is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes (1,2,3 and 4) of the virus have been found.
Shipping
Dry ice
Storage
-80˚C

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Customer Reviews

Customer Q&As
What is a Dengue Virus-Like Particle (Serotype 1)?

A: Dengue Virus-Like Particles (VLPs) are non-infectious particles that closely mimic the structure and characteristics of the serotype 1 strain of the dengue virus. They are composed of viral proteins but lack the viral genetic material, making them safe for use in research and vaccine development.

How are Dengue Virus-Like Particles (Serotype 1) used in research?

A: VLPs are utilized in various research studies to understand the structure, replication, and pathogenicity of the dengue virus. They can be used to study the immune response elicited by the virus, test diagnostic tools, screen antiviral compounds, and evaluate potential vaccine candidates.

How does Dengue Virus-Like Particle (Serotype 1) arise?

A: Dengue Virus-Like Particle (Serotype 1) was produced and tested for stability in the HEK293 Expression System.

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Customer Reviews
A Unique Novel Product

Dengue Virus-Like Particle (Serotype 1) is a unique novel product that can be developed to meet the demand for highly immunogenic, concentrated dengue antigens, and we have used it to good effect in dengue-focused disease research and vaccine development.

United States

06/19/2023

Exceptional Quality

A VLP product of exceptional quality and purity, highly recommended.

United States

04/18/2022

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