Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : RPKZ01
| Cat. No. | RPKZ01 |
| Description | This kit provides a rapid and convenient method for producing high titers of replication-incompetent retroviruses. Separate expression of the essential viral structural genes ensures safety and control over the recombinant constructs by minimizing the risks that arise during cell division and reducing the chance of producing replication-competent virus. |
| Report Gene | High titer & Safe |
| Features |
• High titer: Generate high titers of retroviral particles; • Safe: Generate replication-incompetent retrovirus |
| Applications | Packing retrovectors into retrovirus particles |
A: Retrovirus packaging refers to the process by which a retrovirus assembles and packages its genetic material into viral particles.
A: Yes, like lentiviruses, the genes required for gamma-retroviral packaging and transduction are not encoded by the transfer plasmid but are provided in trans by other plasmids or packaging cell lines.
A: They can. Plasmids encoding SIN gamma-retroviruses lack most of the U3 region of the 3' LTR and are primarily used in gene therapy studies to reduce promoter interference and/or drive high expression of internal promoter transgenes.
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The Supervira™ Retrovirus Packaging Kit includes all the necessary components, eliminating the need to source individual plasmids or cell lines.
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