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Rat Ywhae cDNA Clone(NM_031603.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012759

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Gene Information

Cat. No. CDFR012759
Description NativeORF clone of Rattus norvegicus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (Ywhae) as transfection-ready DNA NM_031603.1
Product Type cDAN Clone
Gene Abbr Ywhae
Species Rat
Vector pCMV6Entry
Target Gene YWHAE
Background This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
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