Mouse YWHAE ORF clone(NM_009536.4)

Name: Mouse YWHAE ORF clone(NM_009536.4)
SKU: CDCL186800
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL186800

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Product Information

Gene Information

Cat. No.	CDCL186800
Description	ORF Clone of Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide DNA.
Product Type	ORF clone
Gene Abbr	YWHAE
Species	Mouse
ORF Size	768bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

YWHAE

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

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