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Rat Xpc ORF Clone(NM_001107874.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR374545

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Product Information

Gene Information

Cat. No. CDCR374545
Product Type ORF Clone
Gene Abbr Xpc
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2802 bp
Vector pCMV6-Entry
Target Gene XPC
Background The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
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