Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


Human XPC Knockdown Cell Line-HeLa

See other products for XPC
Cat.No.
CSC-RK0015
Background
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
XPC
Synonyms
XPC; xeroderma pigmentosum, complementation group C; DNA repair protein complementing XP-C cells; RAD4; xeroderma pigmentosum group C protein; XPCC; p125; mutant xeroderma pigmentosum group C; XP3;
Gene ID
MIM
UniProt ID
Q01831
Chromosome Location
3p25
Pathway
DNA Damage Recognition in GG-NER, organism-specific biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Global Genomic NER (GG-NER), organism-specific biosystem; Nucleotide Excision Repair, organism-specific biosystem; Nucleotide excision repair, organism-specific biosystem;
Function
bubble DNA binding; damaged DNA binding; loop DNA binding; protein binding; single-stranded DNA binding;
Related Products
Cat#
Product Name
Host Cell
Gene Symbol
Species
Price
CSC-SC017582
HEK293 ,CHO, etc.
XPC
Human
CSC-DC017582
HEK293 ,Hela, etc.
XPC
Human
Cat#
Product Name
Titer
Product Size
Species
Price
AD17837Z
>1x 10^9 vp/ml
1 x 0.2 ml
Human
Cat#
Product Name
Size/Form
Species
Price
CDCB171592
------
Danio rerio (zebrafish)

Related Services

Quick Inquiry

Please input "biogene" as verification code.

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2018 Creative Biogene. All Rights Reserved.