Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR006407
| Cat. No. | CDFR006407 |
| Description | NativeORF clone of Rattus norvegicus xeroderma pigmentosum, complementation group A (Xpa) as transfection-ready DNA NM_001106656.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Xpa |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | XPA |
| Background | This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] |
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