Human XPA Knockdown Cell Line-HeLa

Name: Human XPA Knockdown Cell Line-HeLa
SKU: CSC-RK0014
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0014

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0014
Background	This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Target Gene	XPA
Abbr	HeLa-HuXPA Knockdown
Alias	XPA, XP1, XPAC
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	Homo sapiens xeroderma pigmentosum, complementation group A DNA.
Gene Symbol	XPA
Synonyms	XP1, XPAC,XPA
mRNA Refseq	BC014965

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