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Rat Trpm1 cDNA Clone(NM_001037734.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004605

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Gene Information

Cat. No. CDFR004605
Description NativeORF clone of Rattus norvegicus transient receptor potential cation channel, subfamily M, member 1 (Trpm1), transcript variant 1 as transfection-ready DNA NM_001037734.1
Product Type cDAN Clone
Gene Abbr Trpm1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TRPM1
Background This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
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