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Rat Traf4 cDNA Clone(NM_001107017.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006728

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Gene Information

Cat. No. CDFR006728
Description NativeORF clone of Rattus norvegicus Tnf receptor associated factor 4 (Traf4) as transfection-ready DNA NM_001107017.2
Product Type cDAN Clone
Gene Abbr Traf4
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TRAF4
Background This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
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