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Mouse Traf4 cDNA Clone(NM_009423.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL014209

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Gene Information

Cat. No. CDFL014209
Product Type cDNA clone
Gene Abbr Traf4
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene TRAF4
Background This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
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