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Rat Tp73 cDNA Clone(NM_001108696.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008285

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Gene Information

Cat. No. CDFR008285
Description NativeORF clone of Rattus norvegicus tumor protein p73 (Tp73) as transfection-ready DNA NM_001108696.1
Product Type cDAN Clone
Gene Abbr Tp73
Species Rat
Vector pCMV6Entry
Target Gene TP73
Background This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
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