Panoply™ Human TP73 Knockdown Stable Cell Line

Name: Panoply™ Human TP73 Knockdown Stable Cell Line
SKU: CSC-DC016467
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016467

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC016467
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TP73
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TP73 tumor protein p73 [ Homo sapiens ]
Gene Symbol	TP73
Synonyms	TP73; tumor protein p73; P73; p53-related protein; p53-like transcription factor;
Gene ID	7161
Uni Prot ID	O15350
m RNA Refseq	BC117251
Chromosome Location	1p36.3
Function	chromatin binding; damaged DNA binding; double-stranded DNA binding; metal ion binding; p53 binding; protein binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding;
Pathway	Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Measles, organism-specific biosystem; Measles, conserved biosystem; Neurotrophin signaling pathway, organism-specific biosystem;
MIM	601990

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