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Rat Tcirg1 cDNA Clone(NM_199089.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR015206

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Gene Information

Cat. No. CDFR015206
Description NativeORF clone of Rattus norvegicus T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 (Tcirg1) as transfection-ready DNA NM_199089.2
Product Type cDAN Clone
Gene Abbr Tcirg1
Species Rat
Vector pCMV6Entry
Target Gene TCIRG1
Background This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, May 2017]
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