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Mouse Tcirg1 cDNA Clone(NM_001136091.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019580

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Gene Information

Cat. No. CDFG019580
Product Type cDNA clone
Gene Abbr Tcirg1
Species Mouse
ORF Size 2505bp
Size 10 ug
Vector pCMV6Entry
Target Gene TCIRG1
Background This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, May 2017]
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